Greater burdock (Arctium lappa L.)
The burdock extract contains inulin necessary to treat diabetes. Burdock increases the secretion of insulin by the pancreas.
Water and alcohol extracts of burdock inhibit the growth of bacteria and fungi, increase the secretion of bile, pancreatic juice and intestinal juice, have a diastolic and hypoglycemic effect. They increase the secretion of sweat and urine, along with harmful and unnecessary metabolites. Burdock juice strengthens, strengthens immunity, activates tissue renewal processes and regulates sebum secretion. Burdock preparations inhibit inflammation in the body. Arctigenic acid is responsible for the antidiabetic effect, which probably affects the increase of insulin secretion by the pancreas, which is a process disturbed in the case of diabetes. Other studies indicate the activity of sitosterol derivatives present in the root and fruits of Arctium lappa. They lower the sugar level due to the inhibition of β-glucosidase, which delays the absorption of glucose and lowering postprandial hyperglycemia. Scientific research has shown that burdock is rich in lignans that are present in all parts of the plant. According to many researchers, they are responsible for the multidirectional activity of raw materials rich in these compounds. The most important representatives of this group of compounds are arctigenin (in leaves, fruits, seeds and roots), arktin (leaves, fruits, roots), trachelogenin (fruits), lappaol F (fruits, roots, seeds) and diarctigenin (fruits, roots and seeds) . It has been proven that anti-inflammatory action of burdock is based on inhibition of the induced form of nitric oxide synthase (and NOS), on the activity of proinflammatory cytokines, activation of antioxidant enzymes and scavenging of free radicals. Lappaol F, diarctigenin and arctygenin are particularly active in this field. Excessive production of nitric oxide by iNOS is associated with the course of various diseases, such as arthritis, autoimmune diseases or chronic inflammation. Bioactive lignans also show promising anticancer activity, consisting in induction of programmed cell death (apoptosis) on tumor cell lines and inhibition of tumor growth by reducing its tolerance to glucose deficiency. This activity requires confirmation with further research, but it is already known that natural lignans are compounds with high therapeutic potential.
Use: Diabetes, psoriasis, toxin cleansing, digestive disorders
Borgis - Postępy Nauk Medycznych 6/2009, s. 420-428. Piotr Chojnowski, Jaromir Wasyluk, Iwona Grabska-Liberek Cukrzyca – epidemiologia i patogeneza.
Statystyki cukrzycy w Polsce i na świecie. www.cukrzycapolska.pl/cukrzyca/statystyki/ dostęp 23.05.2018