OptiLiver®

This dietary supplement is dedicated to people struggling with issues of the digestive system, as well as for those who want to help the liver in cleansing and regeneration. Opti Liver® is a well-composed blend of natural ingredients that have a positive effect on the functioning of the digestive tract.
The content of ingredients in a daily serving of product 1 capsule 2 capsules
Opti Liverin ® (proprietary formula) 100 mg 200 mg
Rhizomes Picrorhiza kurroa extract 10:1 75 mg 150 mg
Dandelion root extract 10:1 70 mg 140 mg
Burdock root extract 10:1 65 mg 130 mg
Pineapple stalk extract 120:1, including bromelain 20 mg 40 mg
Papain powder 48 mg 96 mg
Burdock fruit extract 10:1 15 mg 30 mg
It's recommended to take 1-2 capsules a day with a water. 60 vegetarian capsules. A detailed description of the extracts can be found in our DiagnoHERB search engine - at www.naturday.pl/search or in the description below.

Digestion disorders and liver regeneration


The disorders affect mostly: stomach, pancreas, liver, small intestine.


The word dyspepsia comes from the Greek language and literally means bad digestion.

Complaints:
  • post-meal feeling of fullness,
  • early feeling of satiety,
  • pain or burning sensations in the epigastrium.

BUT: BESIDES THE FEELING OF DYSPEPSIA, DIGESTIVE DISORDERS AND UNDERNUTRITION OF THE BODY, WE NEED TO POINT OUT THAT - THERE ARE DISEASES THAT DO NOT ARISE FROM MALABSORPTION, BUT BECAUSE OF THE ABSORPTION OF UNFAMILIAR FOOD - PROTEINS THAT CAUSE ALLERGIES OR INFLAMMATIONS IN OUR BODIES.

Dyspepsia can be broadly divided into organic (i.e. recurrent to another disease) and functional.
The causes of organic dyspepsia are specific diseases:
  • peptic ulcer of the stomach or duodenumy
  • gastroesophageal reflux disease
  • chronic pancreatitis
  • INFLAMMATION of the bile ducts and liver
dyspepsia may also be a symptom of cancer, (especially stomach cancer).
Dyspepsia is also a side effect of some drugs
taken chronically, such as:
  • non-steroidal anti-inflammatory drugs,
  • antirheumatic drugs,
  • iron and potassium preparations,
  • antibiotics.

If you can not detect any disease that causes your dyspepsia, your doctor determines the diagnosis of functional dyspepsia.

The causes of functional dyspepsia are not explained.

Various hypotheses are assumed (eg, disturbed contractility of certain segments of the gastrointestinal tract, weakened reaction of the gastrointestinal tract to certain external stimuli and others).

There are two categories of functional dyspepsia:
  • postprandial disorders syndrome
  • epigastric pain syndrome.


How often does dyspepsia disease occur?

Dyspepsia is very common all over the world. Roughly 20-30% of the population have periodic (more frequently or constantly (less often) reported symptoms. About 40% of organic dyspepsia diagnosis - are detected by specific (above-mentioned) causes, and a majority (around 60%) are diagnosed as functional dyspepsia.
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Liver functions

There is a transformation of many substances: lipids, carbohydrates and proteins. The liver is also an organ with important immune properties.

In a nutshell, we can distinguish the following liver functions:

  • carbohydrate management – he liver generates, stores and releases glucose, so it is a large, very dynamic reservoir of basic energy;
  • fat metabolism – the liver converts carbohydrates and proteins into fats, synthesises lipoproteins, phospholipids and cholesterol (used in 80% for the production of bile acids), as well as decomposes lipids into fatty acids;
  • protein production and management – 85% of all proteins found in the plasma are produced in the liver, including albumin and numerous coagulation proteins (including prothrombin); it also forms amino acids necessary for further syntheses and, as a result of the breakdown of amino acids, ketoacids and ammonia;
  • Collecting reserve supplies of vitamins: A, D, B12 and iron
  • detoxifying functions – this applies to the neutralisation of various toxins, including alcohol and ammonia (transformation into urea), as well as coupling and degrading hormones, transforming drugs, etc.Xenobiotics and collaboration with detoxifying herbs (!!!)
  • haem transformation – heme is part of hemoglobin and other protein compounds, is converted to bilirubin ((in 70-80% it comes from hemoglobin heme released in cells of the reticuloendothelial system). Bilirubin combined with albumin after transfer to the liver and disconnection of the albumin molecule is coupled to the glucuronic acid residues and - as soluble in water - excreted into the bile through the hepatocyte bile diarrhea. After passing the bile into the ileum and large intestine, bilirubin undergoes transformation due to the bacteria found there, undergoing transformation into the urobilinogen. About 20% of this bilirubin derivative is absorbed by the intestinal wall into the blood circulation and is captured by the liver, from where it is excreted in the bile and - in small amounts - in the urine. In a healthy human, the total bilirubin concentration is 1 mg / dl (ie 18 μmol / l), of which free, unconjugated bilirubin, insoluble in water (but fat-soluble), found in connection with the albumin transporting it, over 80% of the total circulating bilirubin;
  • bile production – bile is a complex product, essential for fat digestion. 250-1100ml is produced daily. It contains, in addition to water, phospholipids, cholesterol, fatty acids, bilirubin, bile acids and electrolytes. The hepatic bile contains cholic acid and chenodeoxycholic acid (primary bile acids), whereas deoxycholic and lithocholic acids (secondary bile acids) are the result of changes of primary bile acids in the intestine, which are carried out by bacteria deposited there;
  • immunological functions – one of the most important functions of the liver is phagocytosis, that is, it absorbs various particles coming from tissues or getting in from the outside, primarily with blood from the portal vein. These are crumbling fragments of cells, denatured proteins - products of inflammatory processes, immune complexes, lipoproteins, viruses, bacteria, fungi and parasites. They are degraded in phagocytic cells, i.e. hepatic macrophages (Browicz-Kupffer cells), which (being in connection with these functions in the state of arousal) secrete inflammation mediators, including cytokines necessary for the proper formation of immune response. For this reason, the liver is an organ playing a large role in various types of infections, including sepsis, performing neutralizing functions in relation to microorganisms.
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"Medycyna Praktyczna" access 05/04/2018. Liver - structure and functions.
Prof. dr hab. Jacek Juszczyk - Medical University of Karol Marcinkowski in Poznan


Liver dysfunction:
  • metabolic functions
  • weakened detoxification
  • inflammatory changes
  • obstructed outflow of bile
  • as in cirrhosis of abnormal blood circulation in the abdomen and collateral circulation - dangerous esophageal varices.

Pancreas functions
Ok. 80-85% of the organ's mass are vesicles that perform exocrine function, and the remaining 15-20% are responsible for the
intra-exocrine function.
They constitute about 2% of the organ mass of the pancreatic islets, being clusters of endocrine cells A, B, D and PP, secrete insulin as well as glucagon(and somatostatin and pancreatic polypeptide.) Exocrine pancreatic function consists in the production of digestive enzymes. The rate of protein synthesis in the pancreas is huge, as it is only 0.1% body weight produces 13 times more protein than the liver and the reticuloendothelial system, which together account for about 4% of body weight.

Functions of the small intestine
  • production of intestinal juice, i.e. digestive juice consisting of exfoliated intestinal epithelial cells and a solution containing digestive enzymes, such as proteases that degrade proteins and oligopeptides to amino acids; the secretion of intestinal juice is hormonally stimulated by the influence of food pulp
  • digestion of food - proteins are digested by trypsin and chymotrypsin, fat breaks down lipase, and carbohydrates - amylase , as a result of these processes macronutrients are broken down into components and can be absorbed into the blood, and along with it transported to every cell of the body
  • nutrient absorption
In the large intestine:
  • the final process of forming feces takes place.
  • there is a final stage in the absorption of water, electrolytes and mineral salts from food debris.
  • There are symbiotic bacteria that produce vitamin K and some B vitamins.

Problems, related diseases or symptoms of diseases of the gastrointestinal tract in which we use supplements of herbal extracts,

  • Dyspepsia, heartburn.
  • stomach and duodenum ulcers.
  • Enterocolitis
  • Poisonings - chemical pollution in the environment and food, xenobiotics, body poisoning,
  • intestinal flora and skin disorders,
  • loosening connections between intestinal cells - intestinal leaks,
  • penetration of allergenic proteins by damaged enterocytes,
  • recurrent weakness of immunity related to intestinal disorders.
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OptiLiver®

This dietary supplement is dedicated to people struggling with issues of the digestive system, as well as for those who want to help the liver in cleansing and regeneration. Opti Liver® is a well-composed blend of natural ingredients that have a positive effect on the functioning of the digestive tract.

Ingredients:

Opti Liverin®

Proprietary formula from Prunus avium L. and dandelion root supports the liver purification and helps the liver to detoxification and regeneration.

Rhizomes Picrorhiza kurroa extract

is a rich source of flavonoids, polyphenols, vitamins, phytosterols and carotenoids, which have a beneficial effect on the work of the whole organism, with particular emphasis on the digestive system..

Properties: hepatoprotective - protective for liver parenchyma and stronger than silymarin.
stabilises the membrane structure, hinders the penetration of toxins into hepatocytes; stimulates nuclear polymerase and protein translation. bitter tonic herbs, stimulating digestion, with bile disorders, antipyretics
It is a rich source of flavonoids, polyphenols, vitamins, phytosterols and carotenoids, which have a beneficial effect on the work of the whole organism with special regard to the digestive system.
The most important biologically active components of Picrohaiza kurroa are iridoid glucosides (Picroside I, II) called Kutkin, acetophenone derivatives (androsine, apocynin, picein); Cucurbitacin, glycoprotein polymers. In experimental studies carried out in vitro and in vivo, it was proven thatPicrorhiza kurroa protects the liver from the harmful effects of toxin
Amanita, galactosamine, carbon tetrachloride, ethanol, aflatoxin B1, paracetamol and thioacetamide. In comparative studies with silymarin, the disease has turned out to be an equally effective or more effective hepatoprotective agent, but less research has been devoted to this drug than silymarin.
anti-inflammatory effects of Picrorhiza kurroa are explained by its inhibitory effect on neutrophilic granulocytes, macrophages and mast cells. Apocynin, which is a component of this plant, inhibited the in vitro production of free radical compounds by neutrophils, without compromising their ability to chemotaxis and phagocytosis.
The rate of decrease of bilirubin and liver enzymes was significantly higher in the group of people treated with Picrorhiza kurroa. In clinical studies, powdered Picrorhiza kurroa was administered three times a day for two weeks to 15 patients with HBsAg-negative hepatitis B (while 17 patients were given a placebo) All Picrorhiza kurroa hepatoprotective mechanisms are not well researched, but antioxidative activity and the ability to reproduce glutathione cellular resources are in the foreground.
Not only protects but ... Picrorhiza kurroa also has the ability to stimulate liver regeneration, increasing protein synthesis and nucleic acid production.

Dandelion root extract (Taraxacum officinale)

Well-known and liked even by children - dandelion - root extract

Burdock root extract (Arctium lappa Linn.)

They increase the secretion of sweat and urine, along with harmful and unnecessary metabolites.
It strengthens immunity, activates tissue renewal processes and regulates the secretion of sebum.
It has been proven that anti-inflammatory action of burdock is based on inhibition of the induced form of NOS (nitric oxide synthase), on the activity of proinflammatory cytokines, activation of antioxidant enzymes and scavenging of free radicals. Excessive production of nitric oxide is associated with the course of various diseases, such as arthritis, autoimmune diseases or chronic inflammation.

Bioactive lignans also show promising anticancer activity, consisting in induction of programmed cell death (apoptosis) on tumor cell lines and inhibition of tumor growth by reducing its tolerance to glucose deficiency. This activity requires confirmation with further research, but it is already clear that natural lignans are compounds with high therapeutic potential.

Pineapple stalk extract 1 (Ananas comosus), bromelain

It is an exception among enzymes that break down proteins because it goes undamaged by the digestive tract and is absorbed by the body in its original form.

Papain powder (Carica papaya L)

It is a substance similar to human pepsin. It participates in the breakdown of proteins and supports digestion with eg chronic pancreatitis. Papain digested parasite proteins presented in the gastrointestinal tract to albuminosis and peptones.
In medicine, from ages, a papain has been used as an antiparasitic agent (eg in lambliose) that works by digesting the body of a parasite. Also it decomposes sediment and tartar.

Sour Cherry (Prunus Cerasus Mill.)

Properties:
ntioxidant effect. anti-inflammatory and inhibit the production of uric acid. Extract of common cherry fruit contains vitamin C and Melatonin, which helps to regulate the natural cycle of the body\'s activity and increase the efficiency of sleep. According to the research, cherry extract shortens the time of falling asleep by almost 20 minutes. Main relationships. melatonin, carotenoids, hydroxycinnamic acids and several groups of flavonoids, including anthocyanins, as well as quercetin.

Use:
  • insomnia
  • gout,
  • inflammatory condition of digestive tract
Literature available on request and in our search engine
www.naturday.pl/prosearch
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