Rhizomes Picrorhiza kurroa extract
is a rich source of flavonoids, polyphenols, vitamins, phytosterols and carotenoids, which have a beneficial effect on the work of the whole organism, with particular emphasis on the digestive system..
hepatoprotective - protective for liver parenchyma and stronger than silymarin.
stabilises the membrane structure, hinders the penetration of toxins into hepatocytes; stimulates nuclear polymerase and protein translation. bitter tonic herbs, stimulating digestion, with bile disorders, antipyretics
It is a rich source of flavonoids, polyphenols, vitamins, phytosterols and carotenoids, which have a beneficial effect on the work of the whole organism with special regard to the digestive system.
The most important biologically active components of Picrohaiza kurroa are iridoid glucosides (Picroside I, II) called Kutkin, acetophenone derivatives (androsine, apocynin, picein); Cucurbitacin, glycoprotein polymers. In experimental studies carried out in vitro and in vivo, it was proven thatPicrorhiza kurroa protects the liver from the harmful effects of toxin
Amanita, galactosamine, carbon tetrachloride, ethanol, aflatoxin B1, paracetamol and thioacetamide. In comparative studies with silymarin, the disease has turned out to be an equally effective or more effective hepatoprotective agent, but less research has been devoted to this drug than silymarin.
anti-inflammatory effects of Picrorhiza kurroa are explained by its inhibitory effect on neutrophilic granulocytes, macrophages and mast cells. Apocynin, which is a component of this plant, inhibited the in vitro production of free radical compounds by neutrophils, without compromising their ability to chemotaxis and phagocytosis.
The rate of decrease of bilirubin and liver enzymes was significantly higher in the group of people treated with Picrorhiza kurroa. In clinical studies, powdered Picrorhiza kurroa was administered three times a day for two weeks to 15 patients with HBsAg-negative hepatitis B (while 17 patients were given a placebo)
All Picrorhiza kurroa hepatoprotective mechanisms are not well researched, but antioxidative activity and the ability to reproduce glutathione cellular resources are in the foreground.
Not only protects but ... Picrorhiza kurroa also has the ability to stimulate liver regeneration, increasing protein synthesis and nucleic acid production.